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dna_interaction_with_a_benzimidazole-containing_ligands [2012/06/20 10:33] niki [Designed of the GC-recognizing ligand] |
dna_interaction_with_a_benzimidazole-containing_ligands [2014/01/25 04:45] (current) |
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====== DNA interaction with a benzimidazole-containing ligands ====== | ====== DNA interaction with a benzimidazole-containing ligands ====== | ||
+ | <sup>The work done on the [[Abalone]] program.</sup> | ||
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There are a large number of substances that interact with DNA. In general, these are proteins carry out a variety of biological functions. Most proteins interact with DNA in a wide groove of the double helix. That is not surprising, since a wide groove is more accessible and provides a greater variety of contacts, which can be used to build as a general interaction as well as recognition of unique sites. | There are a large number of substances that interact with DNA. In general, these are proteins carry out a variety of biological functions. Most proteins interact with DNA in a wide groove of the double helix. That is not surprising, since a wide groove is more accessible and provides a greater variety of contacts, which can be used to build as a general interaction as well as recognition of unique sites. | ||